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KMID : 0613320130190010014
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Journal of the Korean Bone and Joint Tumor Soceity
2013 Volume.19 No. 1 p.14 ~ p.19
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Inflammatory Myofibroblastic Tumor of Extremities
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Kong Chang-Bae
Lee Jeong-Dong
Lee Jung-Uk
Song Won-Seok
Cho Wan-Hyeong
Koh Jae-Soo
Jeon Dae-Geun
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Abstract
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Purpose: We analyzed the oncologic characteristics and outcome of patients with inflammatory myofibroblastic tumor of extremities.
Materials and Methods: Among the soft tissue tumor patients who were treated between 1999 and 2012, 5 patients who were pathologically confirmed as the inflammatory myofibroblastic tumor of extremities were analyzed retrospectively.
Results: There were 1 man and 4 women with mean age of 44 years (37-55 years). The average follow up was 34.6 months (8-87 months). All patients underwent surgical treatment. Only 1 patient had wide resection margin and remaining 4 had marginal (3) or intralesional (1) resection margin. All of 4 patients without wide resection margin developed local recurrence at 10.3 months (8-19 months). Malignant transformation to fibrosarcoma was occurred in 2 patients who developed local recurrence, and 1 patient developed multiple metastases to lung, liver and lymph nodes and expired at 37 months. Three of 5 patients had tumor location abutted to or invasion to major arteries and 1 patient had tumor invading sciatic nerve.
Conclusion: It is observed that inflammatory myofibroblastic tumor of extremities is usually located near the major neurovascular structure. Wide resection should be considered as the initial surgical treatment because this tumor showed a high local recurrence rate and possibility of malignant transformation.
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KEYWORD
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inflammatory myofibroblastic tumor, extremities, margin, wide resection
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